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Bell’s Palsy
Bell’s Palsy

Bell’s Palsy

Last Updated June 28, 2025

Definition

Bell’s palsy is an idiopathic, acute-onset peripheral facial nerve (CN VII) palsy, most commonly attributed to reactivation of HSV-1 at the geniculate ganglion, leading to inflammation and nerve compression. It characteristically affects both the upper and lower face, resulting in complete hemifacial weakness—including the inability to wrinkle the forehead.

CN VII also handles:

  • Motor: facial expression
  • Taste: anterior 2/3 tongue
  • Parasympathetics: lacrimation, salivation
  • Sensory: external ear

Pathophysiology

  • Inflammation at the geniculate ganglion compresses the facial nerve.
  • HSV-1 reactivation is most likely, but other triggers include:
    • VZV (Ramsay Hunt)
    • CMV, EBV
    • Rarely: Influenza vaccine (Swiss intranasal), COVID-19, mumps
  • Autoimmunity, ischemia, and microvascular neuropathy also theorized (esp. in diabetics).
💡

Goldfrank’s reminds us that some environmental or drug triggers have been proposed, but causality is unclear.

Differential Diagnosis

Key Neuroanatomy

  • Peripheral facial palsy: Affects forehead and lower face (due to lesion distal to nucleus).
  • Central (UMN) lesion: Spares forehead (due to dual cortical innervation).
💡

"The upper face has dual cortical innervation. Only a peripheral lesion knocks it all out.”

From Clinicalmonster.com
From Clinicalmonster.com
Innervation of the Facial Muscles, (from EBMconsult.com)
Innervation of the Facial Muscles, (from EBMconsult.com)

Bell vs. Stroke

Task
Bell’s Palsy
Central (Stroke)
Raise eyebrows
Weak
Normal
Smile
Weak
Weak
Close eyes tightly
Incomplete
Normal
Forehead involvement
Present
Spared
Other neuro signs
Absent
Common (dysarthria, limb weakness, ataxia)
💡

Mislabeling a pontine stroke as Bell’s is one of the most common ED neuro misses. Don't shortcut the CN exam.

Red Flags and other diagnoses

The presence of any additional symptoms especially neurologic should prompt reconsideration of Bell’s palsy and a broader differential.

Feature
Think...
Forehead spared
Stroke (esp. cortical)
Vesicles in ear/mouth
Ramsay Hunt (Varicella Zoster Virus)
Bilateral
GBS, Lyme, sarcoid, HIV
Hearing loss or tinnitus
Cerebellopontine angle tumor
Facial numbness
Trigeminal involvement = NOT Bell’s
Recurrent episodes
Tumor, sarcoidosis, MS
Progressive weakness
Tumor or MS
Other neuro deficits (e.g. ataxia, vertigo)
Brainstem stroke or MS
Faical Numbness
Trigeminimal Involvement
Recent tick bite
Lyme disease
Recurrent otitis media
Temporal bone or ear pathology
💡

Consider a bedside glucose test in patients with diabetes or risk factors—Bell’s is more common in this group, and hypoglycemia can mimic focal neuro deficits.

ED Management

History and Physical

  • Ask about time course: rapid vs progressive
  • Full cranial nerve and neuro exam—don’t skip strength, sensory or cerebellar testing
  • Otoscopy: Ramsay Hunt, otitis, or cholesteatoma?
  • Parotid exam: masses → facial nerve schwannoma or cancer

Testing (if indicated)

  • None if classic Bell’s Palsy
  • Consider further workup if no improvement by 3 weeks, recurrent/progressive or other red flags previously mentioned
  • Outpatient electromyography (delayed 9–20 days) for prognostication, not acute ED use

Treatment within 72 hours

Medication
Dose
Duration
NNT
Prednisone
60–80 mg PO daily
7 days
~10
Prednisolone
1 mg/kg/day PO
7–10 days
~10
Valacyclovir
1 g PO TID
7 days
~19 (with steroids)
Acyclovir
400 mg PO 5x/day
7 days
~19 (with steroids)

Corticosteroids are the cornerstone of Bell’s palsy treatment, with the strongest benefit seen when started within 72 hours of symptom onset. The NNT is 10 to prevent one case of incomplete recovery, based on high-quality meta-analyses. Early treatment improves facial nerve recovery and reduces long-term complications like synkinesis.

Recommended regimens include:

  • Prednisolone 60 mg daily × 5 days, then taper
  • Prednisolone 25 mg BID × 10 days
  • Oral steroids are equally effective as IV, even in severe cases.
💡

Start steroids early. Consider adding antivirals in moderate to severe cases—benefit is small but likely safe.

Adding antivirals (e.g., valacyclovir) offers a modest, borderline-significant benefit, with an NNT of 19. Antivirals alone do not improve outcomes and are not recommended as monotherapy. Combination therapy may be more beneficial in severe cases (House-Brackmann grade V–VI), but evidence is limited.

💡

In patients with renal impairment or age >65, consider baseline creatinine, carefully renally dosing and advise hydration with valacyclovir .

Eye care is an underutilized but essential part of Bells Palsy management and post-visit care. Facial nerve dysfunction in Bell’s palsy leads to incomplete eyelid closure (lagophthalmos) and impaired blink reflex, which reduces tear distribution and increases exposure of the cornea. This sets the stage for corneal desiccation, exposure keratitis, abrasions, and ulcers—which can develop quickly and may lead to permanent vision loss if untreated. The risk of corneal injury is not related to how severe the facial paralysis looks, but rather how much eyelid closure is lost—even mild weakness can result in inadequate protection.

Recommended Intervention
Rationale
Artificial tears (frequent use)
Maintain daytime corneal hydration and tear film stability
Lubricating ointment at bedtime
Prevents overnight drying when blink reflex and lid closure are absent
Eye patch or moisture shield at night
Provides mechanical protection and reduces evaporative loss
Taping the eyelids closed
Alternative if patch not tolerated; should be taught properly to avoid corneal abrasions
💡

If the patient develops eye pain, irritation, redness, or blurred vision, refer urgently to ophthalmology—they may need advanced interventions.

Expectations for Recovery at 3-6 months

Most patients begin to show initial signs of recovery within 2–3 weeks, with continued improvement over 3 to 6 months.

Presentation
Recovery w/o Steroids
Recovery w/ Steroids
All Bells Palsy
71%
Incomplete paralysis
94%
97%
Complete paralysis
61%
83%

Poor Prognostic Indicators

These patients may recover more slowly or incompletely:

  • Age > 60
  • Complete facial paralysis at onset
  • Loss of taste
  • Pain beyond the ear

Counseling Points for the ED

  • Set realistic expectations—even with treatment, recovery takes time.
  • Emphasize eye protection
  • Arrange outpatient follow-up (neurology or ENT)

Disposition

Scenario
Disposition
Action Steps
Classic Bell’s palsy (sudden, unilateral, complete facial weakness with forehead involvement, no other neuro findings)
Discharge
- Start steroids (± antivirals)- Eye protection (tears + ointment + patch) - Arrange outpatient follow-up (PCP, neurology, or ENT in 1 week)
Incomplete eyelid closure (lagophthalmos)
Discharge
- Emphasize aggressive eye protection - Ophthalmology follow-up if pain, redness, or vision changes
No improvement after 3 weeks (on follow-up)
Outpatient neuro/ENT referral
- MRI with IAC if not already done - Consider EMG
Atypical features (bilateral, progressive, recurrent, or partial facial sparing)
Discharge with workup OR consider admission (case-dependent)
- MRI brain with IAC - Labs - Neuro/ENT follow-up
Signs of corneal involvement (pain, redness, blurred vision)
Urgent ophthalmology referral or consult
- Immediate intervention to prevent ulceration - Consider ED ophthalmology consult if available
Systemic illness or unclear diagnosis (e.g., stroke not ruled out, meningitis, CPA tumor)
Admit
- Full neuro workup- MRI/MRA- Consult neurology

Resources

  1. Bell’s Palsy – Core EM. Brennan Chang, https://coreem.net/core/bells-palsy/
  2. Bell’s Palsy in the ED – County EM. Warshaw D. EM Principles Blog. https://blog.clinicalmonster.com/2020/07/16/bells-palsy-in-the-ed/
  3. Baugh RF, Basura GJ, Ishii LE, et al. Clinical practice guideline: Bell’s palsy. Otolaryngol Head Neck Surg. 2013;149(3 Suppl):S1-S27. doi:10.1177/0194599813505967.
  4. Chou’s Electrocardiography in Clinical Practice. 6th ed. Philadelphia, PA: Elsevier; 2008.
  5. CorePendium – Bell Palsy. Khoujah D, et al. EM:RAP; 2024. https://www.emrap.org/corependium/chapter/recvMlu7VuFBIv6x4
  6. Decision Making in Emergency Medicine: Biases, Errors and Solutions. Raz M, Pouryahya P, eds. Academic Press; 2021.
  7. de Almeida JR, Al Khabori M, Guyatt GH, et al. Combined corticosteroid and antiviral treatment for Bell palsy: a systematic review and meta-analysis. JAMA. 2009;302(9):985-993. doi:10.1001/jama.2009.1243.
  8. Gagyor I, Madhok VB, Daly F, Sullivan F. Antiviral treatment for Bell’s palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2019;9:CD001869. doi:10.1002/14651858.CD001869.pub9.
  9. Gronseth GS, Paduga R. Evidence-based guideline update: Steroids and antivirals for Bell palsy: Report of the Guideline Development Subcommittee of the American Academy of Neurology. Neurology. 2012;79(22):2209-2213. doi:10.1212/WNL.0b013e318275978c.
  10. Heckmann JG, Urban PP, Pitz S, Guntinas-Lichius O, Gágyor I. The diagnosis and treatment of idiopathic facial paresis (Bell’s palsy). Dtsch Arztebl Int. 2019;116(41):692-702. doi:10.3238/arztebl.2019.0692.
  11. Lockhart P, Daly F, Pitkethly M, et al. Antiviral treatment for Bell’s palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2009;(4):CD001869.
  12. Madhok VB, Gagyor I, Daly F, et al. Corticosteroids for Bell’s palsy (idiopathic facial paralysis). Cochrane Database Syst Rev. 2016;7:CD001942. doi:10.1002/14651858.CD001942.pub5.
  13. Minor Emergencies. Buttaravoli P, Stair TO. 4th ed. Philadelphia, PA: Elsevier; 2017.
  14. Rosen’s Emergency Medicine: Concepts and Clinical Practice. Marx JA, Hockberger RS, Walls RM, eds. 8th ed. Philadelphia, PA: Elsevier; 2014.
  15. Sullivan F, Daly F, Gagyor I. Antiviral agents added to corticosteroids for early treatment of adults with acute idiopathic facial nerve paralysis (Bell palsy). JAMA. 2016;316(8):874-875. doi:10.1001/jama.2016.10160.
  16. Tintinalli’s Emergency Medicine: A Comprehensive Study Guide. Tintinalli JE, Ma OJ, Yealy DM, et al, eds. 9th ed. New York, NY: McGraw-Hill; 2020.
  17. Yoo MC, Soh Y, Chon J, et al. Evaluation of factors associated with favorable outcomes in adults with Bell palsy. JAMA Otolaryngol Head Neck Surg. 2020;146(3):256-263. doi:10.1001/jamaoto.2019.4312.
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